🦠 🔬 🌱 🧬
Lesson

What Is Life?

What do bacteria, oak trees, mushrooms, and humans all have in common? Let's investigate.

🔍
Driving Question
If a virus can replicate, respond to its environment, and even evolve — what's missing that keeps it from being truly alive?
🔬 Learning Science Focus 🖼️ Dual Coding 🏗️ Scaffolding 🗂️ Concept Formation ✅ Retrieval Practice ⚖️ Load Management
📋 MA STE Standards · Grade 6 6.MS-LS1-1 6.MS-LS1-2
6.MS-LS1-1 Provide evidence that all organisms (unicellular and multicellular) are made of cells.
6.MS-LS1-2 Develop and use a model to describe the function of a cell as a whole and ways the parts of cells contribute to the function.

What Makes Something Alive?

Here are five things. Some are alive. Some are not. One is genuinely debated by scientists. Click each card — what do you think?

🔥
Fire
Alive?
Not Alive
Grows and uses energy — but has no cells, can't reproduce, and doesn't maintain homeostasis. Just chemistry.
🦠
Virus
Alive?
Debated
Can replicate and evolve — but only by hijacking another cell. Has no cells of its own.
🤖
Robot
Alive?
Not Alive
Responds and moves, but has no cells, doesn't grow, and cannot reproduce.
🌱
Seed
Alive?
Alive
Looks dormant — but it's made of cells and can grow, reproduce, and respond to its environment.
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Bacterium
Alive?
Alive
One cell. Eats, grows, responds, reproduces. All six characteristics — check.
Scientists ran into the same problem. To solve it, they identified six characteristics that every living thing shares. If something meets all six — it's alive. Miss even one, and it doesn't qualify.
01 🦠
Made of Cells
Every living organism is built from at least one cell. A unicellular organism runs entirely on a single cell; a multicellular organism is built from many cells working together.
02
Obtain and Use Energy
Living things need fuel to power every life process. Plants capture energy from sunlight; animals break down food. Without a usable energy source, life stops.
03 🌱
Grow and Develop
Organisms increase in size and change in form over their lifetime — from a tiny seed into a towering tree, or from a single fertilized cell into a full human body.
04 👶
Reproduce
Living organisms can produce offspring. Reproduction can be sexual (two parents combine genetic material) or asexual (one parent makes a copy of itself).
05 👁️
Respond to Stimuli
Organisms detect and react to changes in their environment. A plant bends toward light. A bacterium swims away from a toxin. Any change that triggers a response is called a stimulus.
06 ⚖️
Maintain Homeostasis
Living things constantly regulate their internal conditions to stay stable — your body shivers to generate heat and sweats to cool down. This internal balancing act is called homeostasis.

The Discovery of Cells

Once scientists agreed on the six characteristics, a deeper question emerged: what are living things actually made of? Scientists eventually discovered the answer through centuries of microscope observations, forming the foundation of modern biology.

For most of human history, cells were completely invisible — too small to detect without magnification. The invention of the microscope in the 1600s changed that, and with it, our entire understanding of what life actually is.

NO MATTER HOW DIFFERENT THEY LOOK — Bacterium Oak Tree Mushroom Human ALL MADE OF CELLS
I 🔬
All living things are made of cells
From the smallest bacterium to the largest whale, every organism on Earth is built from one or more cells. There are no known exceptions.
II 🧱
The cell is the basic unit of life
A cell is the smallest unit that can carry out all the processes of life on its own — taking in energy, responding to the environment, and reproducing.
III 🔁
All cells come from existing cells
Cells don't appear from nothing. Every new cell is produced when an existing cell divides — connecting every living thing to an unbroken chain of life stretching back billions of years.
These three statements make up Cell Theory — one of the most important frameworks in all of science. Understanding cells means understanding life. The next question scientists asked: are all cells the same?

One Cell or Many?

Once scientists confirmed that all living things are made of cells, a surprising discovery followed: some organisms run their entire lives on just a single cell. Others are built from trillions. Both are completely alive.

Unicellular
One Cell, Every Job
One cell performs every life function itself.
Bacteria · Amoeba · Paramecium · Yeast
Multicellular
Many Cells, Shared Jobs
Specialized cells work together in tissues and organs.
Humans · Oak Trees · Jellyfish · Mushrooms
Big idea: Multicellular organisms survive because different cells specialize for different jobs. This is called division of labor — instead of one cell doing everything, many cells share the work.
Feature Unicellular Multicellular
Number of cells One cell only Many cells — sometimes trillions
How it works One cell handles everything — eating, moving, reproducing Cells specialize and work together in tissues and organs
Examples Bacteria, amoeba, paramecium, yeast Humans, oak trees, mushrooms, jellyfish
Cell type Can be prokaryotic or eukaryotic Always eukaryotic
Complexity Simpler — one cell carries every life function More complex — division of labor between specialized cell types
Visible to naked eye? Usually not Usually yes
A single amoeba eats, moves, senses its environment, and reproduces — all with one cell. This raises the next question: if cells can be so different in number, are they also different in structure?

Two Major Cell Types

Not all cells are built the same way. Scientists discovered that the single biggest structural difference — the one that separates all of life into two camps — is where a cell stores its instruction manual.

Every cell carries DNA — the instructions for how to build and run a living thing. But where that DNA is stored is what makes all the difference.
WHERE IS THE DNA? EUKARYOTIC cytoplasm NUCLEUS DNA enclosed plants · animals · fungi · protists PROKARYOTIC cytoplasm ✕ no nucleus DNA floating freely bacteria
Feature Eukaryotic Prokaryotic
DNA location Enclosed inside a membrane-bound nucleus Floating freely in the cytoplasm — no nucleus
Has a nucleus? Yes No
Examples Plants, animals, fungi, protists (amoeba, paramecium) Bacteria
Unicellular or multicellular? Both are possible Always unicellular
Relative size Generally larger Generally smaller

Back to Viruses

This lesson began with a question about viruses. Now you have the framework — the six characteristics and the cell requirement. Let's apply it.

Viruses CAN...
Carry genetic material (DNA or RNA)
Replicate — inside a host cell
Evolve over time through mutation
Respond to host cell chemistry
Viruses CANNOT...
Build or maintain cells of their own
Reproduce independently — they need a host
Carry out life processes without hijacking another cell
Maintain homeostasis

So — are viruses alive?

Scientists have debated this question for decades. Where do you stand?

You're in good company — some scientists argue viruses should qualify as a form of life, given that they carry genetic material, replicate, and evolve. But most biologists currently classify viruses as nonliving, primarily because they have no cells of their own. Without a host cell to hijack, a virus can't carry out any life processes independently. For most scientists, the cell is the minimum unit of life — and viruses don't meet that threshold.
That's where most scientists currently land — and the central reason is cells. Viruses have no cells of their own. They can only replicate by hijacking the machinery of a living cell. On their own, they can't obtain energy, grow, respond, or maintain homeostasis. The debate isn't completely closed, but the dominant view in biology is clear: without cells, something cannot be considered truly alive.

Vocabulary to Know

Every term below appeared in this lesson. Click any pill to jump to where it was explained.

Organism Made of Cells Obtain and Use Energy Grow and Develop Reproduce Respond to Stimuli Stimulus Homeostasis Unicellular Multicellular Prokaryotic Eukaryotic Nucleus Cytoplasm

What Is Life? Quiz

10 questions covering characteristics of life, cell theory, cell types, and viruses. Answer every question, then submit.

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More Learning

The lesson is just the beginning — push the definition further, test your skills, or explore the edge cases.